Peptide Active Data Details
Basic Peptide Information
DICL ID
DICL_Pep_04592
Ion Channel
Small conductance calcium-activated potassium channel protein 2
Peptide Function
Blocker
Gene Name
KCNN2
Activity Data (nM)
IC50
0.0733 nM
Ki
Not available
EC50
Not available
Kd
Not available
Biologically Active
Not specified
Sequence Information
Peptide Sequence
CNCKAPETALCARRCQQH
Peptide UniProt Accession
UniParc
UPI0000035420
Peptide Synonyms/Alias
[GTPL2311; Apamin; synthetic; >=97% (HPLC); Apamin; from bee venom; >=95% (HPLC)]
Peptide Species
Apis mellifera (Honeybee)
Peptide Name
Apamin
CAS Number
24345-16-2
Experimental Conditions
pH
pH 7.4
Holding Potential (mV)
−100 mV
Temperature
Room Temperature
Test Method
Patch-clamping
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Ion Channel Information
Gene Abbreviation (ABB)
KCa
Ion Channel UniProt Accession
Source Organism
Homo sapiens (Human)
References & Disease Information
Disease
Not specified
PubChem CID
URL
Not available
PMID
Patent
Not available